Multiple Functions of Sushi Domain Containing 2 (SUSD2) in Breast Tumorigenesis
نویسندگان
چکیده
منابع مشابه
Multiple functions of sushi domain containing 2 (SUSD2) in breast tumorigenesis.
Routinely used therapies are not adequate to treat the heterogeneity of breast cancer, and consequently, more therapeutic targets are desperately needed. To identify novel targets, we generated a breast cancer cDNA library enriched for genes that encode membrane and secreted proteins. From this library we identified SUSD2 (Sushi Domain Containing 2), which encodes an 822-amino acid protein cont...
متن کاملSignal Transduction Multiple Functions of Sushi Domain Containing 2 (SUSD2) in Breast Tumorigenesis
Routinely used therapies are not adequate to treat the heterogeneity of breast cancer, and consequently, more therapeutic targets are desperately needed. To identify novel targets, we generated a breast cancer cDNA library enriched for genes that encode membrane and secreted proteins. From this library we identified SUSD2 (Sushi Domain Containing 2), which encodes an 822-amino acid protein cont...
متن کاملUniqueness of meromorphic functions dealing with multiple values in an angular domain
This paper uses the Tsuji’s characteristic to investigate the uniqueness of transcen- dental meromorphic function with shared values in an angular domain dealing with the multiple values which improve a result of J. Zheng.
متن کاملReduced expression of sushi domain containing 2 is associated with progression of non-small cell lung cancer.
Sushi domain containing 2 (SUSD2) has been identified as a gene encoding an 822-amino acid protein, which contains a transmembrane domain and functional domains inherent to adhesion molecules. Previous studies have reported that increased expression of SUSD2 has a critical role in tumorigenesis in human breast cancer. However, to the best of our knowledge, SUSD2 expression status and its correl...
متن کاملSUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer
Tumor-associated macrophages (TAMs) play a role in tumor angiogenesis and are recruited into the tumor microenvironment (TME) by secreted chemokines, including Monocyte Chemoattractant Protein-1 (MCP-1/CCL2). Angiogenesis is required to sustain proliferation and enable metastasis of breast cancer (BCa) cells. Understanding the underlying mechanisms of TAM recruitment would allow for the identif...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Cancer Research
سال: 2012
ISSN: 1541-7786,1557-3125
DOI: 10.1158/1541-7786.mcr-12-0501-t